Find the patients your therapy was built for.
Use explainable response and toxicity models across ICIs, ADCs, bispecifics and CAR-T to design smarter trials, read real-world data faster and shape your launch strategy.
Where Cure-IO fits in your pipeline.
Trial enrichment
Score screened patients for likely response and toxicity to build enriched or stratified cohorts, and model the effect on sample size before you commit.
Safety forecasting
Anticipate irAEs, ILD with ADCs, and CRS or ICANS with bispecifics and CAR-T. Plan monitoring intensity by predicted risk.
Real-world evidence
Run the models across RWD cohorts to compare expected and observed response, find under-served subgroups and support HTA submissions.
Combination strategy
Compare predicted benefit and risk across regimens to prioritise combination arms and sequencing.
Co-development
Fine-tune a dedicated model on your trial data under a joint development agreement, with the IP terms agreed up front.
Launch and access
Equip medical affairs with an explainable tool that helps treating centres identify appropriate patients after approval.
From pilot to programme in four stages.
Indication, endpoints and data sources agreed. DPA signed.
Models run on your historical trial or RWD data.
Calibration, subgroup performance and enrichment simulations.
API or on-prem install for live screening.
Drift tracking and quarterly model reviews.
What each model predicts.
| Model | Efficacy outputs | Safety outputs | Status |
|---|---|---|---|
| Immunotherapy (ICI) | Objective response, 12-month PFS, OS hazard | Grade ≥3 irAE, organ-specific irAE (colitis, pneumonitis, hepatitis) | Available |
| Antibody–drug conjugates | Objective response, time on treatment | ILD / pneumonitis, neutropenia, ocular toxicity | Early access |
| Bispecific antibodies | Response, early progression | Cytokine release syndrome grade, ICANS | Early access |
| CAR-T cell therapy | Complete response, durability at 12 months | CRS, ICANS, prolonged cytopenia | In development |
Ready to get started?
Book a demo, or start free in the Sandbox.
See how Cure-IO fits your clinic, your trial or your product. We’ll walk your clinical, data or pharma team through the models in 30 minutes.
Questions?
Regulation, licensing, data handling and how each model works.
Read the FAQs